一项前性,多中心,单臂研究,评估增强现实导航引导的肺结节定位系统的有效性和安全性
Jiandong Mei1, Zetao Liu1, Qingquan Wu2
1Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.
概括
这项研究表明,增强现实 (AR) 导航系统有效且安全地指导肺癌手术中小肺结节 (SPN) 的定位. 该AR系统实现了95.28%的本地化成功率,证明了其临床实用性.
科学领域:
- 肺部病理学 肺部病理学
- 手术技术 手术技术
- 医疗成像医学成像
背景情况:
- 低剂量计算机断层扫描肺癌查发现越来越多的小肺结节 (SPN).
- 精确,快速和安全地定位SPNs对于成功的手术切除至关重要.
- 现有的本地化方法在精度和安全性方面可能存在局限性.
研究的目的:
- 评估一种新的增强现实 (AR) 导航导向肺结节 (PN) 定位系统的有效性和安全性.
- 评估系统在视频辅助胸部手术 (VATS) 之前促进SPN定位的性能.
主要方法:
- 进行了一项前性,多中心,单臂临床试验.
- 使用AR导航软件和PN标记系统进行了手术前SPN定位.
- 定位成功率,时间,到结节的距离,设备性能和并发症是主要和次要终点.
主要成果:
- 在106名患者中95.28%的局部化成功,超过了91%的客观绩效标准.
- 平均定位时间为3.1分钟,从结节到定位器的平均距离为5毫米.
- 在98.11%的患者中,软件性能被评为优秀,没有观察到与本地化相关的并发症.
结论:
- 该AR导航导向PN定位系统展示了显著的有效性和安全性.
- 这项技术有助于精确地定位SPN用于VATS切除.
- 该系统代表了对最小侵入性肺癌治疗的有希望的进步.
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