结构网络拓和非常早产的年轻成年人的认知控制
Merle J Marek1, Dieter Wolke2, Christian Sorg3
1Psychological Methods and Statistics, Department of Psychology, Carl von Ossietzky Universität Oldenburg, Germany.
NeuroImage. Clinical
|January 25, 2026
概括
非常早产 (<32周孕期) 的个体在认知控制方面表现出持久的缺陷,并在成年时减少了大脑网络的整合. 这些发现凸显了对非常早产个体的持续支持的需要.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 医疗成像医学成像
背景情况:
- 非常早产 (<32周妊娠期) 造成长期神经发育结果的风险.
- 认知控制和大脑网络拓对于适应性功能至关重要.
- 纵向研究对于了解VPT分娩的持久影响至关重要.
研究的目的:
- 研究VPT出生对26岁的认知控制和结构性大脑网络拓学的长期影响.
- 在VPT和全期 (FT) 个体中检查认知控制和大脑网络特征之间的大脑行为关联.
- 确定潜在的干预目标,以减轻早产导致的神经发育影响.
主要方法:
- 利用了来自巴伐利亚纵向研究 (BLS) 的数据,包括61名VPT和79名FT个体.
- 通过多组确认因素分析评估认知控制.
- 通过扩散权重的MRI,曲谱学和图形理论分析分析了结构性大脑网络拓.
主要成果:
- 满期的个体在认知控制速度上得分明显高,与非常早产组相比 (0.742 SD差异,p=0.001).
- 非常早产的小组表现出结构性网络集成的减少,体现在较低的全球效率和平均程度.
- 在网络隔离 (集群系数) 中没有发现任何显著的群体差异.
结论:
- 非常早产与成年期持续的认知控制缺陷和受损的结构性大脑网络集成有关.
- 在这个队列中,结构性大脑网络特征与认知控制能力没有显著联系.
- 调查结果强调,需要对非常早产的个体进行持续的支持和干预,以解决持久的神经发育后果.
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