上肢复杂性二次性至疹:以PRISMA为指导的系统病例审查
Francisco Jover-Diaz1, Lucia Parra-Muñoz2, Mar Trigueros-Rocamora2
1Miguel Hernández University, Infectious Diseases Unit, Spain; San Juan University Clinical Hospital, Alicante, Spain.
Journal of the neurological sciences
|January 25, 2026
概括
带状疹 (HZ) 可能导致罕见的上肢病,主要发生在老年人中. 早期诊断和多模式治疗改善了结果,尽管一些患者经历了持久的影响.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 临床医学 临床医学
背景情况:
- 带状疹 (HZ) 相关的plexopathy是一种罕见的神经并发症.
- 它主要影响老年人,现有的文献仅限于分散的病例报告.
- 关于其发病率,病理生理学,管理和预后,仍然存在重大知识差距.
研究的目的:
- 系统地分析已发表的临床上肢性病例二次性疹 (HZ).
- 澄清HZ相关病的流行病学,临床特征,诊断方法,治疗方法和结果.
- 通过使用严格的方法来综合个体患者数据来解决知识差距.
主要方法:
- 按照PRISMA-IPD指南进行了系统审查.
- 搜索了PubMed,Scopus和EMBASE (2000-2025) 的病例报告/HZ相关的上肢麻症系列.
- 提取的数据包括人口统计,临床,电生理学和成像发现,治疗和结果.
主要成果:
- 分析了来自60篇文章的123名患者 (平均年龄为69.5岁).
- 大多数病例涉及混合运动/感官缺陷 (C5-C6皮肤病),糖尿病和免疫抑制作为常见的并发病.
- 在47%的病例中观察到完全康复;27%的病例有持续的后果. 延迟诊断,免疫抑制,轴突EMG模式和70岁以上的年龄与更糟糕的结果有关.
结论:
- 本综述提供了与HZ相关的手臂病症的全面综合.
- 强调早期临床和电生理学诊断和多式联络治疗的重要性.
- 强调需要标准化诊断方案和前性研究,以提高患者管理和预后.
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