使用基于记录的软件估计的抗菌药物使用量与基于药物包装废弃物清单的估计值的比较
L C B Juliano1, Z Rodriguez1, G G Habing2
1Department of Large Animal Clinical Science, Michigan State University, E. Lansing, MI 48824.
Journal of dairy science
|January 25, 2026
概括
牛奶农场的抗菌剂使用量 (AMU) 可以通过群体记录和药物包装数据准确地测量. 这项研究表明,这些方法为有效的抗菌药物管理提供了一致的AMU估计.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 动物科学动物科学
- 公共卫生 公共卫生
背景情况:
- 准确测量抗微生物药物使用 (AMU) 对乳制品农场的抗微生物药物管理至关重要.
- 有各种方法用于AMU评估,需要验证可靠性.
研究的目的:
- 为了比较来自计算机化群体记录的AMU估计与药物包装库存.
- 评估不同时期的AMU测量的一致性.
主要方法:
- 从2023年5月到2024年1月,对25家传统奶牛场进行观察性研究.
- 利用在线抗微生物基准测试程序进行回顾性AMU分析 (12个月).
- 在4个月的时间内,每周两次收集和计数丢弃的药物包装,以预期AMU估计.
主要成果:
- 从群体记录和药物包装方法中估计的AMU之间没有发现显著差异.
- 在最初的12个月后期数据和4个月前期数据之间,AMU估计保持一致.
- 在不同的AMU测量方法之间观察到中等到良好的一致性.
结论:
- 计算机化群体记录和药物包装库存提供了可靠和一致的AMU估计乳制品农场.
- 这些方法足够精确,以理解和管理乳牛群中抗菌素的使用.
- 农场层面的因素,如平价分布,可能会影响特定的抗生素使用模式.
相关概念视频
What are Estimates?
8.2K
It isn't easy to measure a parameter such as the mean height or the mean weight of a population. So, we draw samples from the population and calculate the mean height or mean weight of the individuals in the sample. This sample data acts as a representative measure of the population parameter. These sample statistics are known as estimates.
The estimate for the mean of a sample is denoted by ͞x, whereas the mean of the population is designated as μ. Further, parameters such...
The estimate for the mean of a sample is denoted by ͞x, whereas the mean of the population is designated as μ. Further, parameters such...
8.2K
Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration
206
Glomerular filtration rate (GFR) can be estimated from serum creatinine using the modification of diet in renal disease (MDRD) formula or the chronic kidney disease–epidemiology collaboration (CKD–EPI) equation. Both methods are widely used in clinical practice to assess kidney function and guide treatment decisions.The MDRD equation does not require weight or height measurements and is normalized to the body surface area of 1.73 m², considered the average adult surface area.
206
Estimation of k and VD of Aminoglycosides
227
Aminoglycosides are a class of antibiotics used to treat various bacterial infections. Clinicians must determine the elimination rate constant (k) and volume of distribution (VD) to optimize therapeutic efficacy and minimize toxicity. The k value represents the rate at which the drug is removed from the body, and the VD reflects the degree to which the drug distributes into body tissues. Accurately estimating these parameters allows healthcare professionals to tailor drug dosing to individual...
227
Estimation of the Physical Quantities
7.5K
On many occasions, physicists, other scientists, and engineers need to make estimates of a particular quantity. These are sometimes referred to as guesstimates, order-of-magnitude approximations, back-of-the-envelope calculations, or Fermi calculations. The physicist Enrico Fermi was famous for his ability to estimate various kinds of data with surprising precision. Estimating does not mean guessing a number or a formula at random. Instead, estimation means using prior experience and sound...
7.5K
Estimating Population Mean with Known Standard Deviation
9.6K
To construct a confidence interval for a single unknown population mean μ, where the population standard deviation is known, we need sample mean as an estimate for μ and we need the margin of error. Here, the margin of error (EBM) is called the error bound for a population mean (abbreviated EBM). The sample mean is the point estimate of the unknown population mean μ.
The confidence interval estimate will have the form as follows:
(point estimate - error bound, point estimate +...
The confidence interval estimate will have the form as follows:
(point estimate - error bound, point estimate +...
9.6K
Confidence Interval for Estimating Population Mean
8.8K
A point estimate of the population mean is obtained from a single sample. Such a point estimate does not represent a population well because it needs to account for variability in the population. Single point estimate can also be biased despite the sample being selected randomly. Thus, a point estimate is often unreliable. A confidence interval is needed to reduce this unreliability.
A confidence interval for the mean is a range of values that provides an estimate of the population mean. As the...
A confidence interval for the mean is a range of values that provides an estimate of the population mean. As the...
8.8K


