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具有BCL11B重组的急性白血病:遗传景观,BCL11B表达和治疗反应

Guilin Tang1, Sa A Wang1, Wei Ying Jen2

  • 1Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

Human pathology
|January 25, 2026
PubMed
概括

在T细胞急性白血病中,BCL11B基因的重组具有重要意义. 光学基因组测绘发现了新的合作伙伴,揭示了复杂的结构多样性和关于BCL11B基因激活的挑战性假设. 建议免疫组织化学用于临床评估.

关键词:
在BCL11B表达式中.在BCL11B的重新排列中.MPAL T/M 类型的表型所有的T-ALL.通过光学基因组映射进行基因组映射.合作伙伴的基因 合作伙伴的基因

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