在0.55 T的同位素3D心脏影像成像使用螺旋采样和四维代运动补偿 (4D iMoCo)
Rajiv Ramasawmy1, Ahsan Javed1, Daniel A Herzka2
1Laboratory of Imaging Technology, Cardiovascular Branch, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, USA.
概括
这项研究提出了一种高效的自由呼吸3D心脏MRI技术,使用螺旋获取和运动补偿重建. 该方法在6分钟内达到2毫米的同otropic分辨率,为心脏成像提供了有价值的临床工具.
科学领域:
- 心血管成像 - 心血管成像
- 磁共振成像 (MRI) 是一种磁共振成像技术.
- 医学物理 医学物理
背景情况:
- 同位体3D电影MRI提供了多功能心脏评估,但面临着长时间的重建和获取时间的挑战,特别是在较低的磁场强度.
- 当前的自由呼吸3D电影MRI技术需要优化效率和速度.
- 在0.55T的获取效率最大化对于临床适用性至关重要.
研究的目的:
- 开发和评估一个高效的自由呼吸的3D电影MRI技术在0.55T.
- 为了提高心脏MRI的获取和重建效率.
- 为了在临床相关的时间框架内实现高分辨率的同位素3D心脏成像.
主要方法:
- 在0.55T.实现了6分钟的2毫米同位素3D电影螺旋堆平衡稳定状态自由前行 (bSSFP) 采集.
- 使用微小黄金角内平面旋转和可变密度k空间采样.
- 采用4D代运动补偿 (4D iMoCo) 重建,将导航器数据用于呼吸运动分辨率.
主要成果:
- 4D iMoCo 重建时间为20分钟.
- 与线性采样相比,可变密度采样减少了人工物,并增加了221±99%的信号噪声比.
- 测量结果与二维卡特西安参考数据有很好的一致性,心室体积和射出分数有轻微偏差.
结论:
- 开发了一种高效的自由呼吸3D心脏MRI技术,可在6分钟内获得2毫米的同位素成像,并在0.55T时进行20分钟的重建.
- 拟议的方法显示了减少文物和提高图像质量的潜力.
- 这种技术可以作为心脏成像的有价值的临床工具.
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