患有双相情感障碍的围产期患者的精神病和产科结局:一个单一机构研究的研究
Kierstin S Utter1, Tamahara Gonzalez-Campos2, Katherine M Moore1
1Department of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, USA.
Journal of affective disorders
|January 25, 2026
概括
怀孕期间的肥胖和精神病医院住院史增加了怀孕中患有双相情绪障碍 (BD) 的孕妇情绪发作的风险. 这些因素,以及创伤史,也与不良的产科结果相关.
科学领域:
- 围产期心理健康问题
- 生殖精神病学是一种精神病学.
- 双极性障碍研究研究
背景情况:
- 患有双相情感障碍 (BD) 的人在产周期间面临不良精神病和产科结果的风险增加.
- 识别与这些风险相关的临床因素对于改善患者护理至关重要.
研究的目的:
- 确定与患有双相情感障碍的个体患有不良精神病和怀孕相关结果的风险增加相关的临床相关性.
- 为患有BD的围产期患者提供个性化的护理策略.
主要方法:
- 从2017年1月到2023年6月,对电子健康记录 (EHR) 的回顾性审查.
- 包括55个有BD病史和至少一个怀孕的个人.
- 对人口统计学,精神病学,医学和产科病史进行分析,以寻找与情绪发作,妊娠糖尿病和妊娠高血压的关联.
主要成果:
- 怀孕期间的肥胖 (BMI ≥30) 是怀孕期间和产后情绪发作的重要危险因素.
- 精神病医院住院史,并发性焦虑症和怀孕期间使用物质与分娩后情绪发作有关.
- 自伤史,创伤和孕前肥胖与不良产科结果 (妊娠期糖尿病/高血压) 有关.
- 双极性障碍亚型 (I,II或其他) 并没有显著预测精神病的结果.
结论:
- 患有BD的人的怀孕和产后情绪发作与妊娠前肥胖,精神病史和物质使用等因素有关.
- 不良的产科结果与创伤史和孕前肥胖症有关.
- 虽然BD亚型不是预测性的,但在个性化围产期护理建议中应考虑病史的严重程度.
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