单极电压映射用于预测脉冲场消去过程中的损伤耐用性
Jonathan Na1, Monisha Krishna Murthy1, Helena Lopez-Martinez1
1Houston Methodist Hospital.
Heart rhythm
|January 25, 2026
概括
单极电图 (u-EGM) 可以预测脉冲场切除 (PFA) 后的持久性病变. 0.4mV的单极电压值表明成功的,持久的剥离区域.
科学领域:
- 电力生理学 电力生理学
- 心血管切除技术的使用.
- 生物医学工程 生物医学工程
背景情况:
- 单极电图 (u-EGM) 在脉冲场切除 (PFA) 后评估病变耐用性方面表现有前途.
- 验证u-EGM参数对于可靠评估PFA结果至关重要.
研究的目的:
- 为了验证u-EGM的电压值,表明PFA诱导的病变.
- 确定这些u-EGM变化对长期损伤耐久性的预测值.
主要方法:
- 用达斯林导管接受PFA的患者获得了单极和双极电压图.
- 在u-EGM S波损失和单极电压之间进行了相关性分析 (ROC).
- 损伤耐用性在单极电压方面进行了评估,食道EGM作为替代品.
主要成果:
- 单极电压值≤0.4mV准确预测了S波损失,这意味着持久的"核心"病变.
- 具有较高电压的光环区域显示出恢复的潜力;双重PFA应用产生了更大,更持久的病变.
- 在重制程序中,单极电压≥0.4mV预测导电恢复,表明有不完全除的区域.
结论:
- 一个单极电压≤0.4mV与u-EGM上的终端S波损失相结合,可靠地识别了持久的切除区域.
- 单极映射为PFA病变的耐用性提供了宝贵的见解,并可以指导程序优化以提高有效性.
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