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Updated: Jan 27, 2026

Using Phage Display to Develop Ubiquitin Variant Modulators for E3 Ligases
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Using Phage Display to Develop Ubiquitin Variant Modulators for E3 Ligases

Published on: August 27, 2021

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通过菌体显示与环E3 RNF38进行直角的ubiquitin转移级联的工程,以揭示其对核运输的调节

Li Zhou1, In Ho Jeong1, Hang Li2

  • 1Department of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA, 30303, USA.

The Journal of biological chemistry
|January 25, 2026
PubMed
概括

我们开发了一种使用菌体显示的新方法来识别环E3无素合酶的基质,特别是RNF38. 这种方法揭示了RNF38的存在.

关键词:
E3 无处不在的合酶戒指域名 戒指域名乌比奎丁是一种存在的药物.菌体显示器可以显示菌体.蛋白质工程工程 蛋白质工程

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