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Updated: Jan 27, 2026

Measuring Enzymatic Activity of Neurodevelopmental Disorder-Associated Deubiquitylating Enzymes via an In Vitro Ubiquitin Chain Cleavage Assay
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Measuring Enzymatic Activity of Neurodevelopmental Disorder-Associated Deubiquitylating Enzymes via an In Vitro Ubiquitin Chain Cleavage Assay

Published on: September 27, 2024

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研究K48/K63异型乌比基链组装中的酶基质相互作用

Gajendra Singh1,2, Hitendra Negi1, Aravind Ravichandran1

  • 1National Center for Biological Sciences, Tata Institute of Fundamental Research, Bengaluru 560065, India.

Biochemistry
|January 26, 2026
PubMed
概括

乌比奎链合成对于细胞信号传递至关重要. 这项研究揭示了E2-25K酶如何形成分支的泛素链,突出了不同细胞信号的酶基质相互作用的立体特异性.

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