协同使用FAIMS和IMS与MS/MS结合,有效地探测蛋白质的结构多样性

Kaiqun Wu1,2,3, Rong Liu1,2,3, Zhonghan Hu1,2,3

  • 1Institute of Mass Spectrometry, Zhejiang Engineering Research Center of Advanced Mass Spectrometry and Clinical Application, Ningbo University, Ningbo 315211, P. R. China.

概括

研究人员开发了一种新的3D仪器,结合了场非对称波形离子运动谱学 (FAIMS) 和离子运动谱学 (IMS),以分离和识别细胞C蛋白离子的不同结构. 该方法使用质谱测量证实了不同的蛋白质对应物,为结构分析提供了强大的工具.

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