基于磁共振成像的前列腺组织形态与国际前列腺症状评分和前列腺动脉栓塞后最大尿流率的变化之间的关联
Chen Wang1, Kun Liang1, Jiasheng Qin1
1Department of Interventional Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Diagnostic and interventional radiology (Ankara, Turkey)
|January 26, 2026
概括
多参数MRI表型预测前列腺动脉栓塞结果在良性前列腺增生. 在PAE之后,腺主导形态显示出尿路症状和尿流率的最佳反应.
科学领域:
- 放射学 放射学是一门学科.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 医疗成像医学成像
背景情况:
- 良性前列腺增生 (BPH) 是一种常见的疾病,导致下泌尿道症状.
- 前列腺动脉栓塞 (PAE) 是BPH的有效治疗方法.
- 在PAE中预测治疗反应对于患者管理至关重要.
研究的目的:
- 为了确定基线多参数MRI (mpMRI) 定义的前列腺形态表型是否与BPHPA后国际前列腺症状评分 (ΔIPSS) 和最大尿流率 (ΔQmax) 的变化相关.
主要方法:
- 对152名接受PAE的患者进行了手术前的mpMRI后期分析.
- 前列腺形态根据T2加权成像将其分类为腺主导,肌层主导或混合.
- 结果 (ΔIPSS, ΔQmax) 在PAE后3,6,12和24个月评估.
- 使用多变量回归和子组分析进行统计分析.
主要成果:
- 所有的表型都显示了PAE后的Qmax和IPSS的改善.
- 腺主导形态表现出最显著和最早的改善,在6个月达到顶峰.
- 压力主导和混合表型的改善较小,延迟,在12个月达到顶峰.
- 腺体形态始终与更高的ΔQmax相关,并与基线症状严重程度相互作用,以预测增强的ΔIPSS.
结论:
- 基线mpMRI定义的前列腺形态与PAE后的临床结果有关.
- 腺主导形态学预测了尿路症状和流量的更优越和更持久的改善.
- 基于MRI的表型可以作为PAE患者分层的实用成像生物标志物.
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