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Updated: Jan 27, 2026

Novel RNA-Binding Proteins Isolation by the RaPID Methodology
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通过连接的微球菌核酶在核糖体上映射RNA结合蛋白

Chia Yi Yao1, Simpson Joseph1

  • 1Department of Chemistry and Biochemistry, University of California at San Diego, 9500 Gilman Drive, La Jolla, California 92093-0314, United States.

Biochemistry
|January 26, 2026
PubMed
概括

我们开发了一种新的方法 - - 连接微球菌核酶映射 (TM-map) - - 以可视化RNA结合蛋白相互作用. 这种技术准确地绘制了蛋白质-RNA结合部位的地图,揭示了对脆弱X精神迟缓蛋白的洞察力.

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