[对超声波估计胎儿体重和双胞胎妊娠中的生物识别的参考值 - 全国队列]
Enav Yefet1, Etty Daniel-Spiegel2, Zohar Nachum3
1Department of Obstetrics and Gynecology, Tzafon Medical Center, Poriya, Israel, Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel.
Harefuah
|January 26, 2026
概括
这项研究确定了对以色列人口双胞胎怀孕的超声波估计胎儿体重 (sEFW) 和生物识别的参考值. 这些新的生长曲线有助于诊断双胞胎的胎儿生长异常,改善怀孕护理.
科学领域:
- 周围生理学 周围生理学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 胎儿超声波检查 胎儿超声波检查
背景情况:
- 与单独怀孕相比,双胞胎怀孕面临的生长异常风险增加.
- 准确的,局部化的参考值对于诊断双胞胎胎的异常胎儿生长至关重要.
- 现有的增长图表可能不能充分代表多样化的以色列双胞胎人口.
研究的目的:
- 在双胞胎怀孕中确定超声波估计胎儿体重 (sEFW) 和生物识别测量的人口特异性参考值.
- 为改善以色列双胞胎怀孕中胎儿生长的诊断和管理提供基础.
主要方法:
- 一个多中心的回顾性纵向分析sEFW和生物识别数据从7,060胎儿 (18,248测量) 在双胞胎怀孕 (2010-2022).
- 使用哈德洛克1985年公式进行sEFW计算.
- 采用非参数的量子通用添加模型 (QGAM) 来构建生长曲线,包括在≥34周怀孕时分娩的双胞胎,不包括重大异常.
主要成果:
- 为以色列人口在双胞胎怀孕中开发了sEFW和生物识别的综合生长曲线.
- 分析显示,不同类型的胸膜和妊娠年龄子组 (≥36周) 的生长模式相似.
- 排除高度不一致的双胞胎 (>30%) 并没有显著改变整体生长曲线.
结论:
- 介绍了以色列双胞胎胎生长评估的第一个本地定制的参考值.
- 这些参考值对于准确诊断胎儿生长异常和随后对双胞胎怀孕进行管理至关重要.
- 这些发现对以色列卫生政策和双胞胎怀孕护理临床实践有重大影响.
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