糖尿病患者的胰岛素抵抗指数和牙周炎:一项基于全国人口的全国性研究
Yuri Kim1, Ji-Eun Kim2, Ki-Ho Chung1,2,3
1Chonnam National University School of Dentistry, Gwangju, South Korea.
Journal of periodontology
|January 26, 2026
概括
像METS_IR这样的胰岛素抵抗指数与糖尿病患者的牙周炎有很强的联系. TyG*WHtR显示了识别高风险个体的最高准确性,有助于早期评估.
科学领域:
- 内分泌学和牙周病学.
- 代谢综合征研究 代谢综合征研究
- 公共卫生与营养
背景情况:
- 胰岛素抵抗是2型糖尿病和牙周炎的重要危险因素.
- 目前对胰岛素抵抗指数和牙周炎的研究主要集中在一般人群中.
- 糖尿病患者非胰岛素抗胰岛素指数与牙周炎之间的关联仍未得到充分研究.
研究的目的:
- 评估糖尿病患者中各种非胰岛素抗胰岛素指数和牙周炎之间的关联.
- 确定这些指标的诊断准确性,以确定糖尿病患者牙周炎风险.
主要方法:
- 分析了来自64,971名成年人的数据 (韩国国家健康和营养检查调查,2010-2018).
- 牙周炎与指数之间的关联评估:TG/HDL,METS_IR,TyG,TyG,经BMI,WC和WHtR调整.
- 使用顺序逻辑回归和ROC分析评估关联和诊断准确性.
主要成果:
- METS_IR显示,与牙周炎的关联最强 (OR=1.401).
- 所有测试的胰岛素抵抗指数都显示,在控制不良的糖尿病 (HbA1c ≥7.0%) 中,牙周炎的几率比率更高.
- TyG*WHtR显示了牙周炎的最高诊断准确率 (AUC=0.6719).
结论:
- 在糖尿病患者中,METS_IR是与牙周炎最强烈相关的指数.
- 在这个人群中,TyG*WHtR为牙周炎提供了最高的诊断准确度.
- 这些指数是早期风险评估和糖尿病患者牙周炎管理的宝贵工具.
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