气球可扩展支架作为急性中风和并列闭塞患者的桥梁治疗
Noelia Rodríguez-Villatoro1,2, David Rodríguez-Luna1, Marian Muchada1
1Unitat d'Ictus Hospital Universitari Vall d'Hebron Barcelona Spain.
Stroke (Hoboken, N.J.)
|January 26, 2026
概括
在急性缺血性中风中,使用气球可扩展 (BX) 支架的桥梁治疗,然后用于额外内动脉 (ICA) 损伤的自我扩展 (SX) 支架,减少了出血并发症. 这种方法保持了支架的通透性,而不会增加复缩或重新封闭率.
科学领域:
- 神经学 神经学
- 血管外科 血管外科
- 干预性放射学 干预性放射学
背景情况:
- 在急性缺血性中风中与合病变的额外头骨内动脉 (ICA) 病变进行支架,存在技术上的挑战.
- 由于需要双抗血小板治疗,支架的安全性受到争论.
- 这些病例的最佳支架装置,时间和抗血小板策略仍然不清楚.
研究的目的:
- 为了比较自扩展 (SX) 与气球可扩展 (BX) 冠状动脉支架在治疗急性缺血性中风和双重闭塞患者的额外头骨ICA病变中的安全性和有效性.
- 为了评估两个支架组之间的症状性内出血和外ICA通透率.
主要方法:
- 一项回顾性研究包括112名患有急性缺血性中风和双重病变的患者,这些患者于2016年4月至2021年4月期间接受治疗.
- 患者接受了传统的自我扩展 (SX) 支架或气球可扩展 (BX) 支架,在亚急性阶段,BX支架与SX支架休息.
- 评估的主要结局是外ICA通透性和症状性内出血.
主要成果:
- 双抗血小板治疗在SX组 (89.7%) 比BX组 (27.4%) 更常见.
- 与SX支架组 (17.9%) 相比,BX支架组的症状性内出血率显著降低 (4.1%).
- 在手术后24小时,两组之间没有观察到高度缩或重新封闭的显著差异.
结论:
- 使用BX支架和不太激烈的抗血小板疗法进行桥梁疗法,然后进行最终的SX支架,是治疗急性缺血性中风中外ICA病变的可行策略.
- 这种方法导致了较低的症状性出血转变率,而不会影响支架的通透性.
- 这些发现表明,对于管理这些复杂的脑血管病例来说,可能有一个更安全的替代方案.
相关概念视频
Design Example: Strain Gauge Bridge or Wheatstone Bridge
980
The utilization of strain gauges as transducers for converting mechanical strain into electrical signals is a common practice in various engineering applications. These strain gauges are frequently integrated into Wheatstone bridge circuits to accurately measure parameters such as force or pressure. Within this context, each element within the circuit exhibits a resistance that undergoes subtle variations when subjected to mechanical strain. The primary objective is to convert minuscule...
980
Bridge rectifier
1.5K
The bridge rectifier is essential in electronics for efficiently converting alternating current (AC) to direct current (DC). Comprised of four diodes configured in a bridge layout, this rectifier effectively processes both the positive and negative halves of the AC waveform, making it superior to half-wave and full-wave center-tapped rectifiers in terms of voltage regulation and output stability.
Operationally, the bridge rectifier allows current flow through two of its diodes during each...
Operationally, the bridge rectifier allows current flow through two of its diodes during each...
1.5K
Wheatstone Bridge
1.2K
An ohmmeter is a resistance-measuring device. It works by applying a voltage to a resistor of unknown resistance and measuring the current across the resistor. The resistance value is deduced using Ohm's law. Usually, the standard configuration of an ohmmeter comprises a voltmeter or an ammeter. However, such configurations are limited in accuracy because the meters alter the voltage applied to the resistor and the current that flows through it.
Thus, for accurate resistance measurements, a...
Thus, for accurate resistance measurements, a...
1.2K
Cross-bridge Cycle
122.5K
As muscle contracts, the overlap between the thin and thick filaments increases, decreasing the length of the sarcomere—the contractile unit of the muscle—using energy in the form of ATP. At the molecular level, this is a cyclic, multistep process that involves binding and hydrolysis of ATP, and movement of actin by myosin.
122.5K
Tandem Mass Spectrometry
2.4K
Tandem mass spectrometry is a technique that uses multiple mass analyzers in series to obtain a higher selectivity and reduce chemical noise during analyte detection. Instruments with multiple analyzers separated by an interaction cell enable secondary fragmentation and selected study of the fragment ions.Secondary fragmentations occur in the interaction cell and can be induced by various factors. Fragmentation induced by collision with inert gases, such as N2, Ar, He, etc., is called...
2.4K
Gene Therapy
27.4K
Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
27.4K


