COVID-19 影响短期,但不影响90天,机械血栓切除术治疗中风患者的结果
Niklas M Beckonert1,2, Felix J Bode1, Franziska Dorn3
1Division of Vascular Neurology Department of Neurology University Hospital Bonn Bonn Germany.
Stroke (Hoboken, N.J.)
|January 26, 2026
概括
在接受内血管治疗 (ET) 的患者中,COVID-19对短期中风恢复产生了负面影响. 然而,90天后的长期功能结果仍然相似,这表明ET不应该被扣留.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 心血管研究研究心血管研究
背景情况:
- COVID-19与中风发病率增加和较差的结果有关.
- 接受内血管治疗 (ET) 的大血管封闭性中风和COVID-19患者的出院结果更差.
- 这些患者的COVID-19的长期功能影响需要进一步调查.
研究的目的:
- 评估COVID-19对ET治疗的大血管封闭性中风患者90天功能结果的影响.
- 为了比较患有和没有同时患有COVID-19的患者之间的结果.
主要方法:
- 德国中风登记-内血管治疗 (GSR-ET) 数据库的分析.
- 患有和没有COVID-19的患者的倾向性得分匹配 (1:4) .
- 多变量顺序回归分析,以评估90天后的功能结果.
主要成果:
- 在4010名患者中,72人 (1.8%) 在ET期间患有COVID-19.
- COVID-19患者在24小时内显示出更高的NIHSS分数和更差的出院分数 (NIHSS和mRS).
- 尽管短期缺陷,90天的功能结果 (mRS) 在各组之间是相似的 (P=0.34).
结论:
- COVID-19对大血管闭塞中风的ET后短期功能结果产生不利影响.
- 长期 (90天) 的功能结果不受COVID-19的显著影响.
- 在符合条件的患者中,无论COVID-19状态如何,都应考虑进行内血管治疗.
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