在接受血液透析的功能障碍患者中评估药物治疗模式:药物利用研究
Dilip Kanjariya1, Anita Sinha1, Hardik Vaniya1
1Pharmacology, Government Medical College, Surat, Surat, IND.
Cureus
|January 26, 2026
概括
这项针对印度血液透析患者的研究发现,高血压和多药的高率,以及非最佳使用仿制药和基本药物的情况. 研究结果强调了在透析护理中需要合理的处方和标准化药物治疗.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 慢性病 (CKD) 和急性损伤 (AKI) 是全球主要的健康问题.
- 印度面临着日益严重的CKD负担,高血压和糖尿病加剧了这种负担,脏替代疗法获得的机会有限.
- 血液透析患者遇到复杂的药物治疗方案和不良药物反应的挑战.
研究的目的:
- 为了评估血液透析患者的药物处方模式.
- 根据世卫组织的处方指标评估药物使用情况.
- 促进在血液透析药物治疗中合理使用药物.
主要方法:
- 在印度古吉拉特州苏拉特进行了为期12个月的横截面观测研究.
- 使用预先设计的病例记录表格,从150名成年血液透析患者获得知情同意和数据收集.
- 使用IBM SPSS统计,版本20进行统计分析.
主要成果:
- 高血压 (64.6%) 和糖尿病 (24.6%) 是主要的并发症;23%的人不知道自己的疾病.
- 每名患者平均处方7.53种药物,常见的是腹腔内红素.
- 心血管 (29.8%) 和胃肠道 (20%) 药物是最常见的;通用药物 (60.17%) 和NLEM (68.76%) 的处方率低于最佳.
结论:
- 血液透析患者高患高血压和多药,大量使用心血管和胃肠道药物.
- 观察到低于最佳的仿制药和基本药物处方率和高注射使用率.
- 在医疗保健机构中药物使用的变化需要合理的处方和药物治疗标准化.
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