双盲随机非劣质性研究,研究喉利多卡因麻醉对EUS的影响
Yuki Fujii1, Kazuyuki Matsumoto1, Kei Harada1
1Department of Gastroenterology and Hepatology, Okayama University Hospital, Okayama, Japan.
Endoscopic ultrasound
|January 26, 2026
概括
在患者接受镇静和止痛药时,对内镜超声波 (EUS) 不需要使用利多卡因的喉麻醉. 省略此步骤可以提高患者的舒适度,并可能降低成本.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 麻醉学 麻醉学
背景情况:
- 内镜超声波 (EUS) 通常涉及镇静和止痛药.
- 使用利多卡因的传统喉麻醉可以引起不适和过敏反应.
研究的目的:
- 为了确定是否需要基于利多卡因的喉麻醉,以止痛药镇静下进行EUS.
主要方法:
- 在EUS之前,一项双盲,随机的非劣势性研究比较了利多卡因喷雾 (LG) 与盐水喷雾 (PG).
- 主要结果是EUS耐受性,其次要结果包括患者满意度和程序事件.
主要成果:
- 与利多卡因组 (85%的内镜使用者,90%的患者) 相比,安慰剂组 (88%的内镜使用者,91%的患者) 的EUS耐受性不差.
- 在安慰剂组中,患者满意度显著更高.
- 在其他次要结果中没有发现显著差异.
结论:
- 在服用镇静剂和止痛药时,对EUS不需要使用利多卡因进行喉麻醉.
- 省略利多卡因可能会提高患者的舒适性,减少并发症,缩短手术时间和降低医疗费用.
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