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Updated: Jan 28, 2026

Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors
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固体瘤中的基蛋白和额外终端蛋白:免疫微环境的调节者和新兴的治疗点

Deeksha Sharma1, Grace G Bushnell2, Alexander P Kalman1

  • 1Rogel Cancer Center, University of Michigan, Ann Arbor, MI, United States.

Frontiers in immunology
|January 26, 2026
PubMed
概括

博莫代因和超终端域 (BET) 蛋白质是表观遗传调节者,对癌症干和免疫逃避至关重要. 抑制BET蛋白显示出同时向瘤生长和增强抗癌免疫反应的前景.

关键词:
B 细胞 B 细胞BET 抑制剂 (BETi) 的使用在 NK 细胞中,NK 细胞是 NK 细胞.在T细胞,T细胞.原蛋白和额外终端蛋白 (BET蛋白)与瘤相关的巨细胞 (TAMs)

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