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异常的B细胞反应作为SLE病变发生过程中自身抗体生成和表位组多样化的驱动因素

Fareeha Tariq1,2, Yathavi Charavanmuttu3, Kazi Labiba2

  • 1King's College Hospital, NHS Trust, London, United Kingdom.

Frontiers in immunology
|January 26, 2026
PubMed
概括

皮层扩散驱动全身性红斑狼 (SLE),通过通过自身反应性B细胞多样化自身抗体反应. 新型双标CAR-T疗法提供了一种全面的方法,通过消除等离子体细胞和自身反应性克隆来恢复B细胞自身免疫力.

关键词:
卡特 卡特 卡特一个小小的东西.自主反应的B细胞.标本正在扩散,正在扩散.这就是Rituximab.第三级淋巴状结构 (TLS)

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