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Updated: Jan 28, 2026

Production, Crystallization and Structure Determination of C. difficile PPEP-1 via Microseeding and Zinc-SAD
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对PPEP-3的结构分析和基质分析为Pro-Pro内酸酶特异性的分子基础提供了新的见解

Bart Claushuis1, Fabian Wojtalla2, Lisa Papenhagen2

  • 1Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden 2333 ZA, the Netherlands.

iScience
|January 26, 2026
PubMed
概括

普罗-普罗内酶 (PPEPs) 是细菌酶,可以切割普罗林键. 这项研究揭示了PPEP-3中由关键氨基酸驱动的独特特异性机制,为蛋白酶功能提供了洞察力.

关键词:
生物化学 生物化学生物科学 生物科学生物科学中的方法论.蛋白质组学 蛋白质组学结构生物学结构生物学

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