内膜流量转移器数量对动脉瘤治疗结果的影响:一个多中心研究
Justin E Vranic1, Pablo Harker2, Christopher J Stapleton2
1Department of Radiology Massachusetts General Hospital Harvard Medical School Boston MA.
Stroke (Hoboken, N.J.)
|January 26, 2026
概括
与单个支架相比,多重叠的转流支架在动脉瘤封闭或并发症方面没有显著差异. 最好使用单个支架,除非复杂的病例需要多个支架.
科学领域:
- 神经外科 神经外科
- 干预性放射学 干预性放射学
- 血管外科 血管外科
背景情况:
- 转流支架 (FDS) 用于治疗内动脉瘤.
- 使用多重重叠的FDS是复杂动脉瘤的不断发展的技术.
- 有限的数据存在,比较单个与多个FDS关于有效性和安全性的数据.
研究的目的:
- 为了比较单个和多重重叠的流量转移支架之间的动脉瘤闭塞率和阳性并发症.
- 评估多个流量转移支架结构的安全性和有效性.
主要方法:
- 一个多中心动脉瘤数据库 (2012-2020) 的回顾性审查.
- 包括用单个或多个管道栓塞装置 (PED) 治疗的囊状动脉瘤.
- 最少12个月的血管学和临床随访;主要结局:闭塞率;次要结局:并发症.
主要成果:
- 250名患者接受了一次PED,48名患者接受多次PED.
- 闭塞率没有显著差异 (单个:83.6%与多个:83.4%;P=0.65).
- 与手术相关的并发症没有显著差异 (单个:8.0%与多个:4.2%;P=0.42),包括缺血性中风.
结论:
- 与单个PED相比,多重叠的PED并不能显著改善动脉瘤封闭率.
- 在单个和多个PED之间,与程序相关的并发症没有显著差异.
- 单个PED的使用通常是首选的;多个PED被保留给复杂的病例,如巨大的动脉瘤.
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