关于基底动脉阻塞最佳管理的当前意见:在最好的基础调查之后
Brian Drumm1,2, Soma Banerjee1, Muhammad M Qureshi3
1Stroke Medicine Imperial College Healthcare NHS Trust, Charing Cross Hospital London UK.
Stroke (Hoboken, N.J.)
|January 26, 2026
概括
尽管试验结果中立,但大多数医生倾向于为基底动脉堵塞 (BAO) 提供内血管治疗. 然而,没有,有.
科学领域:
- 神经学 神经学
- 干预神经病学 干预神经病学
- 脑卒中医学 脑卒中医学
背景情况:
- 基础动脉封闭 (BAO) 的管理缺乏明确的指导.
- 之前的试验 (BASICS,BEST) 给出了中立的结果,造成了不确定性.
- 医生对BAO治疗的看法对于未来的研究至关重要.
研究的目的:
- 调查有关BAO管理的当前医生实践和意见.
- 为了确定医生是否认为BAO的进一步随机对照试验 (RCT) 是必要的.
主要方法:
- 一项国际在线调查分发给中风神经病学家和神经干预专家.
- 调查评估了内血管治疗 (EVT) 与最佳医疗管理的临床和成像标准.
- 探索临床医生愿意将患者纳入BAO RCT.
主要成果:
- 超过95%的受访者会为BAO提供EVT,但标准差异很大.
- 大多数医生 (70%) 报告说,在BASICS和BEST试验之后,实践没有变化.
- 对EVT的患者选择因地理位置,专业和收入水平而异.
- 超过80%的人支持进一步的BAO RCT,对试验招生的接受程度不同.
结论:
- 医生在很大程度上保持对EVT对选择BAO患者的疗效的信念,无论之前的试验如何.
- 缺乏对选择标准的共识,需要进一步的研究.
- 基础动脉封闭的进一步随机临床试验得到了中风社区的强烈支持.
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