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Updated: Jan 28, 2026

A 3D Spheroid Model for Glioblastoma
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使用微工程3D瘤芯片模型对CAR-T细胞针对质母细胞瘤进行多模式分析

Kalpana Ravi1, Shannon Trottier2, Obed B Amissah2

  • 1School of Biological and Health Systems Engineering (SBHSE), Arizona State University, Tempe, AZ, 85287, USA.

Bioactive materials
|January 26, 2026
PubMed
概括

研究人员开发了一种芯片上的质母细胞瘤模型,以测试化学抗原受体 (CAR) T细胞治疗脑瘤的方法. 这种新工具精确地模拟了瘤微环境,改善了对CAR T细胞抗质母细胞瘤疗效的临床前测试.

关键词:
在CAR T细胞中,癌症免疫疗法癌症免疫疗法在IL13Rα2中.微流体学 微流体学在T细胞工程方面,T细胞工程在芯片上的瘤 (TOC)

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