狗转移性肺结节的表征在F-氧葡萄糖正子发射断层扫描/计算机断层扫描上
Eric D Y Kim1, Jasmine Gu1, Arata Matsuyama1
1Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.
这项研究表明,虽然18F-FDG PET/CT可以检测狗的肺结节,但需要特定于狗的SUVmax值来准确地确定癌症的阶段. 目前的人类指导方针错误地将许多结节分类为非恶性.
科学领域:
- 兽医瘤学 兽医瘤学
- 诊断成像诊断成像的使用
- 核医学是一种核医学.
背景情况:
- 肺转移是狗癌症死亡的主要原因.
- 传统的成像缺乏对小转移性结节的敏感性.
- 18F-FDG PET/CT提供功能性成像,但缺乏特定于犬类的参数.
研究的目的:
- 通过使用18F-FDG PET/CT.来表征狗肺结节.
- 为了调查结核大小,位置和SUVmax之间的关联.
- 评估当前人类SUVmax指南对狗的有用性.
主要方法:
- 在患有癌症的狗中对109个肺结节进行了回顾性审查.
- 由董事会认证的放射科医生对18F-FDG PET/CT扫描进行分析.
- 对结节大小,位置和SUVmax的统计分析.
主要成果:
- 结节大小 (中位数6.4毫米) 和SUVmax (中位数3.72) 显示出很高的变化.
- 结节大小和SUVmax之间存在正相关性 (τ = 0.526; P < 0.001).
- 人类SUVmax切线错误地将34.9%的结节分类为非恶性.
结论:
- 18F-FDG PET/CT对犬类瘤学有价值,但需要特定物种的参数.
- 特定于狗的SUVmax值对于准确的诊断和分期至关重要.
- 需要进一步的前性研究来完善SUVmax在犬肺结节中的解释.
更多相关视频
11:09High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
Published on: December 16, 2022
05:32Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice
Published on: January 7, 2019
相关概念视频
Positron Emission Tomography
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
Imaging Studies II: Positron Emission Tomography and Scintigraphy
Fundamental Principles of PET
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography
Electron Microscope Tomography and Single-particle Reconstruction
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
Emission Spectra
