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Updated: Jan 27, 2026

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在MicroRNA@neutrophil衍生的微囊中实现双重代谢-炎症调制,实现强大的骨关节炎治疗

Yijun Chen1, Yongbin Wang1, Ruonan Yan1

  • 1State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Advanced Pharmaceuticals and Biomaterials, China Pharmaceutical University, Nanjing 211198, China.

Acta pharmaceutica Sinica. B
|January 26, 2026
PubMed
概括

这项研究引入了一种新型的基因疗法,使用微粒细胞 (MVs) 传递微RNA-140-5p (miR140) 用于骨关节炎 (OA) 治疗. 这种方法有效地减少炎症并恢复软骨,为关节疾病提供了有前途的新疗法.

关键词:
这是一种抗炎症药物.穿透软骨的穿透情况代谢的恒常状态是代谢的恒常状态.这是一个微型RNA.微小片是微小的片.中性粒细胞中性粒细胞.骨关节炎是一种骨关节炎.有协同效应的效应.

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