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Updated: Jan 28, 2026

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血清C-反应蛋白/白蛋白比作为口腔状细胞癌的预后标志物
Sandip V Vasave1, Jyoti D Bhavthankar2, Akshay A Mishra3
1Senior Resident, Grant Government Medical College and Sir JJ Group of Hospitals, Mumbai, Maharashtra, India.
Journal of oral and maxillofacial pathology : JOMFP
|January 26, 2026
概括
血清C反应蛋白 (CRP) 与专蛋白的比率有效预测了口腔状细胞癌 (OSCC) 的进展. 这种炎症标志物有助于对OSCC患者的预后和术后监测.
科学领域:
- 在瘤学瘤学.
- 生物标志物 生物标志物
- 炎症研究 炎症研究
背景情况:
- 系统性炎症对口腔状细胞癌 (OSCC) 的预后产生负面影响.
- 血清C反应蛋白 (CRP) 和白蛋白水平是已知的炎症标志物.
- CRP与白蛋白的比率是OSCC的潜在预后预测指标.
研究的目的:
- 评估血清CRP与白蛋白比率与OSCC临床阶段和组织学等级之间的关联.
- 确定CRP与白蛋白比率作为OSCC中预后生物标志物的有用性.
主要方法:
- 包括35名经组织病理确认的OSCC.患者.
- 测量了血清中CRP,白蛋白的水平,以及它们的比例.
- 将这些水平与临床阶段和组织学等级相关联.
主要成果:
- 血清CRP水平随着OSCC的高级阶段和等级显著增加.
- 血清白蛋白水平显示不显著下降与先进的OSCC阶段和等级.
- 随着OSCC临床阶段和组织学等级的增加,CRP与白蛋白的比率逐渐增加,与阶段有显著的相关性.
结论:
- 血清CRP与白蛋白的比率作为OSCC预后的有价值的血清标记.
- 这种比率可能有助于对OSCC患者的术后监测.
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