草 (Cymbopogon citratus) 补充剂改善了断奶小猪的生长性能,肠道功能和炎症状态
Jing Liang1,2, Zhenmei Zhong3, Aiyang Wang4
1Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China.
Animal nutrition (Zhongguo xu mu shou yi xue hui)
|January 26, 2026
概括
草食补充剂通过调节微生物群组成和增强消化酶活性,显著改善了小猪生长和肠道健康. 这种天然替代品显示出替代动物料中的抗生素使用的前景.
科学领域:
- 动物营养和料科学 动物营养和料科学
- 肠道微生物组研究研究
- 动物生理学 动物生理学
背景情况:
- 动物料中的抗生素增长促进剂正面临着越来越严格的审查,因为存在对抗菌素耐药性的担忧.
- 正在探索天然料添加剂作为抗生素的替代品,以改善动物健康和生产力.
- 草 (Cymbopogon citratus) 具有已知的抗微生物和抗炎性质,这表明在动物饮食中具有潜在的益处.
研究的目的:
- 研究饮食中草补充剂对断奶小猪生长表现,肠道形态和炎症的影响.
- 通过多omics方法 (微生物组学,代谢组学,转录组学) 阐明草作用的潜在机制.
- 评估草作为抗生素增长促进剂的潜在天然替代品.
主要方法:
- 21只断奶小猪被分配给三种饮食治疗:基本饮食,0.1%的草 (LCC) 的基本饮食或0.5%的草 (HCC) 28天.
- 进行了多个omics分析 (微生物组学,代谢组学,转录组学) 的ileal内容和组织.
- 评估了生长性能,肠道形态,肠道微生物群组成,代谢物概况,基因表达和炎症标志物.
主要成果:
- 饮食草显著改善了小猪生长性能和肠道形态 (P < 0.001).
- 草补充剂增加了肠道微生物群的β多样性和像Lactobacillus reuteri这样的有益细菌的丰富性 (P = 0.045).
- 它增强了氨基酸和脂质代谢,提高了营养代谢和免疫信号基因的调节,减少了炎症性细胞因子 (P < 0.001),并增加了脂酶 (P = 0.004) 和素 (P = 0.002) 的活性.
结论:
- 食草有效地改善了断奶小猪的生长,肠道健康,消化功能和炎症状况.
- 草调节肠道微生物组成,增强新陈代谢通路,有助于其有益作用.
- 在生猪生产中,草显示出作为抗生素增长促进剂的安全有效的天然替代品的巨大潜力.
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