死亡后胰腺自解作为早期死亡后间隔的组织学标记:在热带环境中进行的法医解剖研究
Sunon Sripirom1, Vichan Peonim1, Wisarn Worasuwannarak1
1Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Forensic science international. Synergy
|January 26, 2026
概括
死亡后胰腺自解是早期死亡后间隔估计的有用组织学标记,特别是在热带环境中. 虽然它本身并不精确,但当与其他方法相结合时,它有助于法医解剖.
科学领域:
- 法医病理学 法医病理学
- 历史学 历史学 历史学
- 死亡后间隔估计估计
背景情况:
- 准确的死后间隔 (PMI) 估计在法医调查中至关重要.
- 器官的组织学变化为PMI提供了潜在的标志物,特别是在早期阶段.
- 胰腺自解,死后降解过程,已被探索为一个潜在的指标.
研究的目的:
- 在法医解剖中评估死后胰腺自解作为早期PMI的组织学标志物.
- 为了研究胰腺自解 (头部,身体,尾部) 的区域差异.
- 评估胰腺自解在热带环境中的适用性.
主要方法:
- 研究了30个已知PMI<24小时的法医尸检案例.
- 从头部,身体和尾部收集了胰腺组织样本.
- 经过处理和染色的样本 (血素-素) 用于视觉定量自溶性变化.
主要成果:
- PMI显示了所有胰腺区域的自解和平均自解 (p ≤ 0.002) 的显著正相关性.
- 自溶变得可见于死后2小时左右; >50%的自溶在5小时之前没有观察到.
- 在创伤性死亡中,PMI和自解之间的相关性更强.
结论:
- 死亡后胰腺自解提供了对早期PMI有价值的见解.
- 它最好用作多式联络方法中的补充组织学工具,而不是作为唯一的决定因素.
- 这种方法在温暖,潮湿的 (热带) 法医环境中尤为重要.
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