内血管治疗后的d-Dimer水平可以帮助预测急性缺血性中风的结果
Hyo Suk Nam1, Young Dae Kim1, Joonsang Yoo2
1Department of Neurology Yonsei University College of Medicine Seoul South Korea.
Stroke (Hoboken, N.J.)
|January 26, 2026
概括
在接受内血管治疗 (EVT) 的急性缺血性中风患者中,d-二聚合物水平升高预测结果不佳. 高d-二次数独立地与功能状况恶化和EVT后死亡风险增加有关.
科学领域:
- 神经学 神经学
- 血液学 血液学 血液学
- 生物标志物 生物标志物
背景情况:
- d-Dimer表示高凝血,与血栓形成和分离有关.
- 在接受内血管治疗 (EVT) 的急性缺血性中风患者中调查d-dimer的预测价值.
研究的目的:
- 为了评估在急性缺血性中风中接受EVT的患者的d-二次数水平和结果之间的关联.
- 为了确定d-二次体水平是否可以预测EVT后的功能结果和死亡率.
主要方法:
- 分析来自SECRET注册表的数据,重点是接受EVT的患者.
- 根据d-二次体水平,患者被分为三次体.
- 通过NIH中风尺度得分,三个月功能结果 (mRS) 和三种动物的六个月死亡率进行比较.
主要成果:
- 高的d-二次数水平 (三次数3) 与退院时NIH中风量表得分较差有关.
- 较低的3个月功能结果 (mRS ≥3) 在较高的d-二次数三位体中明显更常见 (76.4%在三位体3).
- 高d-二次数独立预测了3个月的不良结果 (OR 4.399) 和6个月的死亡率 (OR 5.441).
结论:
- 血d-二聚合物水平升高预示着神经系统早期恶化.
- 高水平的d-二次体与EVT后3个月的功能性结果不佳有关.
- 增加的d-二元水平独立预测在EVT后6个月内死亡率.
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