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在儿童中破裂的固体伪毛囊瘤:一个20年的单中心经验
Suhyeon Ha1, Soo-Min Jeong1, Hyunhee Kwon1
1Division of Pediatric Surgery, Asan Medical Center Children's Hospital, Asan Medical Center, University of Ulsan College of Medicine, Songpa-gu, Seoul, Republic of Korea.
Frontiers in pediatrics
|January 26, 2026
概括
破裂的固体伪毛囊瘤 (SPN) 在儿童中可能导致腹复发,尽管成像可能表明比确诊的病例更多. 瘤大小和扩散影响风险.
科学领域:
- 儿科瘤学 儿科瘤学
- 手术病理学的外科病理学
- 腹部成像检查 腹部成像检查
背景情况:
- 固体伪巴皮细胞瘤 (SPN) 是一种罕见的胰腺瘤,经过手术切除后的预后通常有利.
- 在SPN中瘤破裂不常见,但可能与腹传播的风险增加有关.
- 关于SPN破裂的数据,特别是在儿科患者群体中,是有限的.
研究的目的:
- 评估SPN破裂儿童的临床病理特征,手术结果和复发模式.
- 在儿科患者中评估破裂的SPN切除后腹膜扩散和复发的风险.
主要方法:
- 七名儿科患者 (<18岁) 的回顾性审查,其中包括经过切除的组织学确认的破裂SPN患者.
- 对临床病理学,手术和随访数据的分析,包括将复发归类为疑似 (放射学) 或确诊 (组织学).
主要成果:
- 所有七名患者都是女性,平均年龄为12岁,中位数瘤大小为7.4厘米.
- 42.9%的破裂是自发的,57.1%的破裂是与创伤有关的. 距离胰腺切除术是最常见的手术 (71.4%).
- 疑似复发发生在71.4%的患者中,但确诊的复发与腹扩散发生在28.6%的患者中,与较大的瘤 (>10厘米) 和周围胰腺扩张相关.
结论:
- 破裂的SPN在儿童中存在真正腹膜复发的风险,成像可能会高估复发.
- 瘤大小和周延伸可能是儿童破裂SPN复发风险分层的指标.
- 完整的手术切除,全面的腹膜评估和长期的患者监测对于管理这种情况至关重要.
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