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Updated: Jan 28, 2026

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

Published on: January 21, 2020

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通过循环添加 [3 + 2] 通过使用Co (II) 作为催化剂进行5‐Phenyl-1H-tetrazole的绿色热水合成:通过响应表面方法 (RSM) 和DFT计算进行统计优化

Joseph Alarcon-Gonzales Del Valle1, Victor Garcia-Villegas2, Julio Santiago-Contreras1

  • 1Department of Organic Chemistry, Faculty of Chemistry and Chemical Engineering, Universidad Nacional Mayor de San Marcos, Lima 15081, Peru.

ACS omega
|January 26, 2026
PubMed
概括

一种新的绿色化学方法通过使用催化剂和水合成5-Phenyl-1H-tetrazole (5-PHTA). 这种环保的方法优化了产量,减少了对环境的影响.

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