在美国暴露于和脑血管死亡率
Xin Wang1, Ziqin Cao1, Kelly M Bakulski1
1Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA, 48109.
Hygiene and environmental health advances
|January 26, 2026
概括
暴露与美国成年人脑血管死亡风险更高有关. 减少环境中的暴露对于公共健康和预防中风至关重要.
科学领域:
- 环境健康 环境健康
- 心血管科学 心血管科学
- 毒理学 毒理学 毒理学
背景情况:
- 脑血管疾病是美国死亡的重要原因之一.
- 环境毒素,如,越来越多地与脑血管风险有关.
- 本研究研究了暴露与脑血管死亡率之间的关系.
研究的目的:
- 调查暴露与脑血管死亡率之间的关联.
- 分析来自美国成年人全国代表性样本的数据.
主要方法:
- 利用了1999-2016年周期国家健康和营养检查调查 (NHANES) 的数据.
- 包括40岁及以上的成年人,死亡率随访至2019年.
- 员工调查加权考克斯的比例危险模型,以评估与脑血管死亡率的联系.
主要成果:
- 脑血管死亡率的风险增加23%与血液中的每一个四分位数间范围的增加有关.
- 尿中的与较高的脑血管死亡率有边际显著的关联.
- 观察到的关联在吸烟者中可能更强,尽管在统计学上并不显著.
结论:
- 暴露与美国人口中脑血管死亡率的增加显著相关.
- 研究结果强调是脑血管疾病的可修改环境风险因素.
- 建议针对烟草控制,饮食法规和环境政策的公共卫生干预措施来减少暴露.
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