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身体活动与中国成年人慢性阻塞性肺病风险相关:一项为期11年的前性研究

Hao Wang¹, Huaidong Du², Lingli Chen³

¹Department of Non-Communicable Diseases Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.

Frontiers in sports and active living

|January 26, 2026

概括

在吸烟男性中,较高的体力活动显著降低了患慢性阻塞性肺病 (COPD) 的风险. 这种保护性关联在女性或非吸烟男性中没有观察到.

科学领域:

公共卫生公共卫生
流行病学流行病学
呼吸系统医学呼吸系统医学

背景情况:

慢性阻塞性肺病 (COPD) 是一个重大的全球健康挑战,对发病率和死亡率做出了重大贡献.
关于身体活动与COPD发病率之间的联系的研究仍然有限,尽管这种疾病对公众健康的影响很大.

研究的目的:

调查身体活动水平与发生COPD事件的风险之间的关联.
为了确定体力活动是否在大量队列中提供对COPD发展的保护作用.

主要方法:

一项前性队列研究,涉及来自中国Kadoorie生物库的49482名参与者 (30-79岁).
使用每天代谢相当的任务小时 (MET-h/day) 量化体力活动,并将其分为四分位数.
考克斯比例危险回归模型被用来分析身体活动和COPD事件之间的关系,平均随访时间为11.5年.

主要成果:

在551,266人年中,确诊了1,470例COPD病例.
与最低四分位数相比,体育活动最高四分位数的参与者显示,与最低四分位数相比,发生COPD的风险降低了30%,特别是吸烟男性 (HR=0.70).
在女性或非吸烟男性中,没有发现身体活动和COPD风险之间的显著关联.

结论:

身体活动与发生COPD的风险有相反的关联,尤其有利于吸烟男性.
这些发现表明,促进身体活动可能是预防COPD在特定人群中的可行策略,例如男性吸烟者.

关键词:

成年人成年人成年人成年人成年人慢性阻塞性肺病慢性阻塞性肺病代谢等价任务代谢等价任务身体活动身体活动这是一个前性研究.

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