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在内血管血栓切除试验中的种族和民族多样性
Gisele Sampaio Silva1,2, Eva Rocha1, Amol Mehta3
1Department of Neurology and Neurosurgery Division of Vascular Neurology and Neurointensive Care Universidade Federal de São Paulo (UNIFESP) São Paulo Brazil.
Stroke (Hoboken, N.J.)
|January 26, 2026
概括
黑人和西班牙裔成年人患中风风险和死亡率较高. 治疗方法的不足利用,如内血管血栓切除术和临床试验中的代表性不足,突出了中风护理中的显著种族差异.
科学领域:
- 神经学 神经学
- 公共卫生 公共卫生
- 临床研究 临床研究
背景情况:
- 急性缺血性中风负担不成比例地影响黑人成年人,发病率和死亡率更高.
- 在美国,黑人和西班牙裔成年人中,血栓消毒疗法和内血管血栓切除术的使用率不足.
- 尽管有联邦多样性倡议,种族和民族少数群体在美国临床试验中的代表性仍然不足.
研究的目的:
- 审查中风发病率和临床护理方面的种族和民族差异,重点关注血管内血栓切除术.
- 描述内血管血栓切除试验中的多样性报告.
- 确定在这些试验中增加多样性的机会和障碍.
主要方法:
- 关于中风差异的现有文献的专题综述.
- 对内血管血栓切除术利用率和临床试验多样性的数据分析.
- 审查全球种族和种族报告标准.
主要成果:
- 黑人和西班牙裔成年人的中风发病率,治疗利用率和临床试验代表性存在显著差异.
- 全球范围内缺乏标准化的种族和种族报告,这使得对试验多样性的评估变得复杂.
- 尽管努力促进研究中的多样性,但代表性不足仍然存在.
结论:
- 解决中风治疗中的种族和民族差异,特别是内血管血栓切除术,至关重要.
- 需要标准化报告和有针对性的策略来改善临床试验的多样性.
- 克服障碍对于确保公平获得中风治疗和参与研究至关重要.
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