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Updated: Jan 28, 2026

A Quick Phenotypic Neurological Scoring System for Evaluating Disease Progression in the SOD1-G93A Mouse Model of ALS
06:49

A Quick Phenotypic Neurological Scoring System for Evaluating Disease Progression in the SOD1-G93A Mouse Model of ALS

Published on: October 6, 2015

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在ALS模型中,ATH-1105可单独减轻多种病理,也可与riluzole联合使用

Andrée-Anne Berthiaume1, Kayla N Kleist1, Sherif M Reda1

  • 1Athira Pharma, Inc., Bothell, WA, United States.

Frontiers in neurology
|January 26, 2026
PubMed
概括

ATH-1105显示为治疗肌缩侧面硬化症 (ALS) 的前景. 这种药物单独或与riluzole结合,在小鼠模型中改善了神经肌肉功能并减少了神经退行,为ALS患者提供了新的希望.

关键词:
这就是ALS.在TDP-43中使用.肝细胞生长因子 肝细胞生长因子神经纤维光链的光链.神经保护神经保护神经变因子的神经变因子瑞卢 (riluzole) 是一种药物.小分子疗法小分子疗法

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