对新加坡对受控人类感染研究的公众态度的伦理分析:可接受性和付款
Barnaby Young1,2,3, Alberto Giubilini4, Xin Hui Sam3
1National Centre for Infectious Diseases, Singapore.
Asian bioethics review
|January 26, 2026
概括
新加坡人很大程度上支持受控人类感染 (CHI) 研究,包括使用SARS-CoV-2的研究. 他们倾向于支付更高的参与者费用,例如每小时SGD30美元,这表明公众的信任可能不仅仅是挑战研究的接受.
科学领域:
- 医学伦理 医学伦理
- 传染病研究 传染病研究
- 公共卫生政策 公共卫生政策
背景情况:
- 新加坡正在启动使用SARS-CoV-2的首个受控人类感染 (CHI) 研究.
- 公众的看法和道德考虑,特别是参与者支付,需要在研究开始前进行评估.
研究的目的:
- 为了衡量公众对新加坡CHI研究的看法.
- 探索对道德问题的态度,特别是对SARS-CoV-2挑战研究的参与者补偿模型.
- 将新加坡人的态度与英国研究中的态度进行比较.
主要方法:
- 为了评估公众对CHI研究的看法,进行了一项调查.
- 该调查包括关于一般CHI研究,SARS-CoV-2特定研究和支付模式的问题.
- 结果与在英国进行的类似研究进行了比较.
主要成果:
- 在新加坡观察到,公众对CHI研究的支持很大,这表明了潜在的社会许可.
- 大多数受访者以前对CHI研究的知识有限.
- 新加坡人更喜欢更高的支付模式 (市场或支付风险),强烈支持每小时30美元SGD.
结论:
- 尽管公众对CHI研究的了解有限,但公众对新加坡CHI研究的支持很大.
- 在研究中对参与者支付的态度与当前的做法不同,有利于更高的激励措施.
- 除了机构信任之外的因素,例如研究的内在价值,可能会影响公众对CHI研究的接受.
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