奇亚里I形:审查和更新当前的治疗选择
Jordan J Lo1, Shuhei Shiino1, Stephen Z Shapiro2,3
1Tulane University School of Medicine, New Orleans, Louisiana, USA.
概括
奇阿里形I型 (CM-I) 治疗侧重于后解压,但手术技巧各不相同. 新兴的微创手术选择对某些CM-I患者来说是有前途的.
科学领域:
- 神经外科 神经外科
- 神经学 神经学
背景情况:
- 奇亚里形I型 (CM-I) 涉及小脑桃体穿过大孔的.
- 病理生理学是复杂的,影响脊节结.
研究的目的:
- 评估CM-I目前的治疗选择.
- 专注于基于证据的临床结果和新兴的外科手术技术.
主要方法:
- 使用PubMed.com进行了全面的文献审查.
- 包括108篇文章:回顾性研究,案例系列,系统审查.
- 搜索的 MeSH 术语:"阿诺德-奇亚里形,第 1 种", "神经膜炎", "阿诺德-奇亚里形*/手术".
主要成果:
- 后腔解压是标准的CM-I手术治疗.
- 在手术技术中存在显著的变化 (硬化整形,桃体缩小).
- 最少侵入性和内镜技术显示有希望的初步结果.
结论:
- CM-I 管理需要一个定制的,以症状为导向的方法,平衡有效性和安全性.
- 针对水脑或不稳定等并发疾病进行个性化手术.
- 至少侵入性手术是选择CM-I患者的有希望的替代方案.
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