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Updated: Jan 28, 2026

Visualization of Endoplasmic Reticulum Subdomains in Cultured Cells
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基于基基质网膜蛋白质稳定调节剂化合物,具有增强的生物活性

Gabriel M Kline1, Lisa Boinon2, Adrian Guerrero1

  • 1Department of Chemistry, The Scripps Research Institute, San Diego, United States.

eLife
|January 26, 2026
PubMed
概括

研究人员确定了新的化合物,通过向蛋白质二硫化物异构酶来增强内分泌网膜 (ER) 蛋白质稳定. 这些化合物有望通过改善ER中的蛋白质加工来治疗蛋白质错折疾病.

关键词:
在ATF6中使用ATF6.生物化学 生物化学化学生物学 化学生物学细胞内膜网膜的内oplasmic网膜.人类 人类 人类 人类 人类 人类 人类这里是鼠标鼠标鼠标鼠标鼠标鼠标.蛋白质的平衡是蛋白质的平衡.小分子分子小分子不折叠的蛋白质反应反应

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