制造大豆蛋白分离物/富科伊丹复合体稳定高内部相皮克林乳液,以提高纳灵的稳定性,生物可用性和3D打印能力
Yubo Cao1, Quanshu Wang1, Tong Sun1
1College of Food Science and Engineering, Nanjing University of Finance and Economics/Collaborative Innovation Center for Modern Grain Circulation and Safety, Nanjing 210023, China. songhaizhaothu@nufe.edu.cn.
Food & function
|January 26, 2026
概括
豆蛋白分离物和富可伊丹复合物产生稳定的高内部相皮克林乳液 (HIPPEs). 这些HIPPE增强了纳林根因的稳定性,生物可用性,并表现出优异的3D打印能力,用于营养药物.
科学领域:
- 食品科学与技术 食品科学与技术
- 材料科学 材料科学 材料科学
- 生物技术是生物技术.
背景情况:
- 高内部相皮克林乳液 (HIPPEs) 是生物活性化合物的先进输送系统.
- 豆蛋白分离物 (SPI) 和富可伊丹 (FUC) 是具有乳液稳定潜力的天然生物聚合物.
研究的目的:
- 开发和表征SPI/FUC稳定HIPPEs,以增强疏水性营养品的输送.
- 评估开发的HIPPE的物理化学,学和微观结构性质.
- 评估HIPPE中封装的纳林根因 (NAR) 的稳定性,生物可访问性和生物活性.
主要方法:
- 用于HIPPE稳定性的SPI/FUC复合物的制备和表征.
- 物理化学分析包括化指数,质学和热稳定性.
- 在紫外线照射和模拟胃肠道消化下对纳灵宁 (NAR) 的封装和稳定性评估.
- 在体外生物可访问性,细胞吸收研究和抗炎性测试.
- 开发的HIPPE的3D打印能力的评估.
主要成果:
- SPI/FUC-HIPPEs在30天内表现出高稳定性,化指数低 (9.12%).
- 风湿学分析显示了类似凝的粘弹性行为,具有出色的厚度回收 (>75%) 和热稳定性.
- 封装NAR显著改善稳定性 (89.94%与57.93%相比),增强生物可访问性 (73.20%),并增加了体外生物可用性 (增加了3.6倍).
- SPI/FUC-HIPPEs表现出优异的抗炎作用和优异的3D打印能力,具有良好的机械强度和形状保真度.
结论:
- SPI/FUC复合物有效地稳定HIPPEs,提供增强的稳定性和控制释放的疏水性营养药物,如naringenin.
- 开发的HIPPE显著提高了纳林根因的稳定性,生物可用性和生物活性,在功能性食品和制药中具有潜在的应用.
- SPI/FUC-HIPPEs卓越的3D打印能力为制造结构化食品和药物输送系统开辟了新的途径.
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