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Updated: Jan 28, 2026

Gene Knock-in by CRISPR/Cas9 and Cell Sorting in Macrophage and T Cell Lines
11:32

Gene Knock-in by CRISPR/Cas9 and Cell Sorting in Macrophage and T Cell Lines

Published on: November 13, 2021

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一种基于CRISPR-Cas9蛋白质的改进方法,用于淘汰昆虫Sf9细胞基因

Miguel Graça1,2, Nikolaus Virgolini1,2, Ricardo Correia1,2

  • 1iBET, Instituto de Biologia Experimental E Tecnológica, Apartado 12, Oeiras, 2780-901, Portugal.

Applied microbiology and biotechnology
|January 26, 2026
PubMed
概括

这项研究为昆虫细胞引入了一种高效的CRISPR-Cas9基因编辑管道,增强生物制药生产. 在Sf9细胞中淘汰Sf-Dronc可以增强细胞灭亡抵抗力,并增加流感病毒样颗粒的产生.

关键词:
它们是花鸟 (Spodoptera frugiperda) 的种类.先进疗法的药物,先进疗法的药物.细胞灭亡 (apoptosis) 是一种死亡的过程.百科病毒表达载体系统的表达载体系统克里斯普尔-Cas9是什么意思细胞系发育的发展.

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