在一个青少年中,T细胞淋巴细胞淋巴瘤呈现B型乳酸和急性损伤
Pelin Abdal Yıldırım1, Seçil Arslansoyu Çamlar2,3, Demet Kocatepe Çavdar4
1Department of Pediatrics, Division of Nephrology, Izmir City Hospital, Bayraklı, Izmir, 35540, Turkey. pelinabdal@outlook.com.
Pediatric nephrology (Berlin, Germany)
|January 26, 2026
概括
儿科急性损伤 (AKI) 很少可能源于T细胞淋巴细胞淋巴瘤透. 通过脏活检和化疗及时诊断对于治疗这种罕见的儿童AKI和乳酸性酸的原因至关重要.
科学领域:
- 儿科脏病学 儿科脏病学
- 儿科血液瘤学
- 在瘤学瘤学.
背景情况:
- 儿童急性损伤 (AKI) 是疾病和死亡的重要原因,通常与脱水,败血症或有毒暴露有关.
- 虽然不常见,但血液性恶性瘤可以入脏,导致AKI.
研究的目的:
- 报告一例罕见的儿童AKI病例,该病例是由T细胞淋巴细胞淋巴瘤直接入脏引起的.
- 要突出儿童AKI中无法解释的乳酸,瘤和血液恶性瘤之间的联系.
主要方法:
- 一个13岁男孩的病例报告,患有AKI,代谢性酸性疾病和高乳酸血症.
- 诊断工作包括成像研究和脏活检.
- 治疗包括化疗.
主要成果:
- 脏活检显示T细胞淋巴细胞淋巴瘤的扩散性脏透.
- 代谢发现表明B型乳酸,归因于华堡效应.
- 在开始化疗后,乳酸水平迅速正常化.
结论:
- 在儿童AKI病例中,应考虑血液性恶性瘤,其中包括无法解释的乳酸和瘤.
- 早期识别,脏活检和迅速的瘤治疗对于改善这种病例的结果至关重要.
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