中心室阻塞性缩中心室动脉短心:电生理学和病理学发现,以及最佳的手术程序
Takashi Nitta1, Shun-Ichiro Sakamoto2, Yuji Maruyama2
1Department of Cardioascular Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, 113-8602, Tokyo, Japan. nitta@nms.ac.jp.
概括
中心室阻塞性缩 (MVOH) 患者患有耐火性心室低心率 (VT) 可能受益于手术干预. 在一项对6名患者的研究中,LV形动脉瘤和冷热的切除有效消除了静脉瘤.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 心脏外科手术 心脏外科手术
背景情况:
- 中心室阻塞性缩 (MVOH) 经常导致耐火性心室低心率 (VT) 和心脏突然死亡.
- 在MVOH中VT的潜在机制和最佳治疗策略仍然不太清楚.
研究的目的:
- 调查MVOH患者静脉瘤的电生理和病理基础.
- 评估该人群中耐火性静脉瘤手术干预的疗效.
主要方法:
- 六名患有MVOH和耐火性静脉瘤的患者接受了手术,包括LV形动脉瘤的内心切除和周围冷热.
- 进行了手术前和手术后的电生理学研究以及切除组织的病理分析.
主要成果:
- 电生理学研究显示,与痕相关的瘤重新进入远端LV动脉瘤是可能的VT机制.
- 没有发生手术或晚期死亡. 在中位数72个月的随访期间,仅在一个患者身上观察到静脉瘤复发.
结论:
- 在MVOH中,VT与与痕相关的LV尾动脉瘤的重新进入有关.
- 结合LV形动脉瘤切除和心肌冷热的手术治疗似乎对MVOH中耐火性静脉瘤有效.
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