结合非侵入性脑刺激和物理治疗,改善退伍军人慢性腰部疼痛的管理:多臂随机对照试验的协议
Frederique Dupuis1,2, Yannick Tousignant-Laflamme3,4, Pascale Marier Deschênes1,2
1Centre for Interdisciplinary Research in Rehabilitation and Social Integration, Quebec, QC, Canada.
JMIR research protocols
|January 26, 2026
概括
这项研究调查了与重复性跨磁刺激 (rTMS) 结合心理知情物理治疗 (PiP) 是否可以改善慢性腰部疼痛 (LBP) 和心理风险因素的退伍军人的身体功能. 结果预计将于2028年6月公布.
科学领域:
- 神经学 神经学
- 物理疗法物理治疗
- 心理学 心理学 心理学
背景情况:
- 慢性腰部疼痛 (LBP) 显著影响退伍军人,标准治疗显示适度有效.
- 焦虑和抑郁等心理因素经常与退伍军人的慢性腰痛同时发生,需要综合治疗方法.
- 心理上知情的物理治疗 (PiP) 通过解决LBP的认知和情绪方面的承诺,但残留症状往往持续.
研究的目的:
- 为了比较与PiP组合的活性重复性跨膜磁性刺激 (rTMS) 与PiP和常规物理治疗 (UP) 的虚假rTMS的疗效,用于患有慢性LBP的退伍军人.
- 评估对疼痛强度,生活质量,抑郁,疼痛灾难化,运动恐惧,自我效能,药物使用和PTSD症状的次要影响.
主要方法:
- 一项三臂并行随机对照试验,涉及96名患有慢性腰痛和并发性心理风险因素的退伍军人.
- 参与者接受8周的活跃rTMS + PiP,假rTMS + PiP或UP.
- 结果通过在线问卷在基线,2,8周和26周进行评估,并使用线性混合模型进行治疗意向分析.
主要成果:
- 招聘正在进行中,截至2025年12月,已有28名参与者注册. 预计2028年6月份将获得完整的结果.
- 该研究假设,与假装的RTMS + PiP和通常的物理治疗相比,活跃的RTMS + PiP将产生更好的结果.
- 数据收集和分析计划持续到2027年12月.
结论:
- 创新的干预措施对于管理退伍军人的慢性LBP至关重要.
- 这项试验将为PiP和rTMS在疼痛管理中的联合作用提供新的证据.
- 积极的发现可能会改善慢性LBP的退伍军人临床实践和提高生活质量.
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