从饮食和酒精诱导的高血糖质血症中可预防的大脑静脉鼻血栓塞:一个说明性的案例
Saaya Maruyama1, Kiyoyuki Yanaka1, Minami Saura1
1Department of Neurosurgery, Tsukuba Memorial Hospital, Tsukuba, Ibaraki.
Journal of neurosurgery. Case lessons
|January 26, 2026
概括
严重的维生素B12和叶酸缺乏会导致脑静脉鼻血栓症 (CVST),这是一种危险的中风亚型. 及时诊断和生活方式干预是管理这种可预防的疾病的关键.
科学领域:
- 神经学 神经学
- 血管医学 血管医学
- 营养神经科学 营养神经科学
背景情况:
- 大脑静脉鼻血栓 (CVST) 是一种罕见的中风亚型,通常具有非特异性症状,导致诊断延迟.
- 过高homocysteinemia 是一个已知的CVST风险因素.
- 获得的维生素B12和叶酸缺乏症可能会导致严重的高血血和CVST,但经常被忽视.
研究的目的:
- 呈现 CVST 的病例,这是严重的维生素 B12 和叶酸缺乏症的次要病例.
- 突出生活方式因素在诱导这些缺陷中的作用.
- 强调彻底的历史记录的重要性,以确定可修改的风险因素.
主要方法:
- 一个44岁的男性患有肥胖和大量饮酒的病例报告.
- 临床表现包括头痛,嗜睡和焦点神经缺陷.
- 诊断工作涉及神经成像和实验室测试,揭示了CVST,严重的超homocysteinemia,以及临界低的维生素B12和叶酸水平.
主要成果:
- 这位患者出现了CVST,双侧静脉梗塞和左侧出血.
- 严重的高homocysteinemia (143.4 nmol/mL) 归因于与生活方式变化相关的维生素B12和叶酸缺乏.
- 用抗凝血剂,维生素补充剂,戒酒和营养咨询治疗导致症状改善,并在30天内使同型氨酸正常化.
结论:
- 严重的维生素缺乏,加剧了生活方式的变化,可以导致显著的CVST.
- 优先考虑详细的病史,以确定可修改的生活方式因素,对于及时诊断和干预至关重要.
- 有效的管理包括解决营养不足和生活方式因素,以使同类氨酸正常化并防止复发.
相关概念视频
Venous Thrombosis I: Introduction
432
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
432
Venous Thrombosis III: Interprofessional Care
306
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
306
Venous Thrombosis IV: Nursing Management
240
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
240
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
335
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
335
Cancer Prevention
8.1K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
8.1K
Venous Return
12.2K
The circulatory system plays a crucial role in ensuring the optimal functioning of the human body. One of its critical components is venous return - the process that completes the blood circulation cycle. This article will delve into the concept of venous return, how it works, and its significance to our health.
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system...
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system...
12.2K


