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研究假设对随机临床试验结果的影响:标准和非劣势随机临床试验之间的比较

Yuanxi Jia1, Yiwen Jiang2, Peng Wu2

  • 1Alice Lee Center for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore (Y.Jia, Y.D.).

Annals of internal medicine
|January 26, 2026
PubMed
概括

具有积极假设的标准RCT (随机临床试验) 显示出比非劣等性RCT (NI-RCT) 更大的效果估计,特别是当盲目化不足时. 标准RCT中的负假设产生了与NI-RCT类似的结果.

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