东南亚的生活质量和多种长期疾病:系统性审查和元分析
Deborah Ikhile1,2, Patrick Highton3,4, Clare Gillies3,4
1Diabetes Research Centre, University of Leicester, Leicester, UK. di46@leicester.ac.uk.
Nature communications
|January 26, 2026
概括
这项审查发现,东南亚多种长期疾病患者报告生活质量降低但良好. 了解生活质量指标对于调整医疗保健系统至关重要.
科学领域:
- 医疗保健服务研究 医疗服务研究
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 多重长期疾病 (MLTCs) 对全球个人和医疗保健系统构成重大挑战.
- 东南亚面临着越来越多的慢性疾病负担,需要对患者的生活质量 (QoL) 有明确的理解.
- 现有的文献缺乏专门针对该地区MLTC种群的QoL措施和结果的系统综合.
研究的目的:
- 系统地审查和综合有关东南亚MLTC患者生活质量指标和结果的证据.
- 确定常用的QoL评估工具,并报告汇总的QoL得分.
- 在不同的文化背景下为管理MLTC提供医疗保健系统适应策略的信息.
主要方法:
- 来自34项涉及11,876名参与者的研究证据的系统审查和综合.
- 对报告在三个或更多队列中相同的QoL得分的研究进行了元分析.
- 在剩余的研究中使用了描述性叙事合成.
主要成果:
- 世界卫生组织"生活质量简报" (WHOQOL-BREF) 和EuroQol5维5级 (EQ-5D-5L) 是最常用的QOL工具.
- 汇总的平均得分表明生活质量降低,但一般良好:WHOQOL-BREF (70.47) 和EQ-5D-5L (0.76).
- 观察到QOL结果的显著异质性,受疾病组合和文化因素的影响.
结论:
- 东南亚的MLTC患者的生活质量处于中等水平,因特定条件和区域背景而有所不同.
- 在选择和应用QOL评估工具时,必须考虑东南亚人口中的文化细微差别和特定疾病概况.
- 医疗保健系统需要量身定制的方法来有效地解决MLTC的复杂性,并改善该地区患者的治疗结果.
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