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Updated: Jan 28, 2026

A Double Humanized BLT-mice Model Featuring a Stable Human-Like Gut Microbiome and Human Immune System
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Published on: August 30, 2019

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效应器-宿主互动组图将健康肠道微生物组中的III型分泌系统与免疫调节联系起来

Veronika Young1, Bushra Dohai1, Hridi Halder1

  • 1Institute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Munich, German Research Center for Environmental Health, Neuherberg, Germany.

Nature microbiology
|January 26, 2026
PubMed
概括

综合性肠道细菌,Pseudomonadota,拥有完好无损的III型分泌系统 (T3SS),可以将效应蛋白注入人体细胞中. 这些相互作用影响宿主信号,并与克罗恩氏病等疾病有关.

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