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在机器人辅助激进前列腺切除术中Z形卧卧姿的有效性:随机对照试验的研究协议
Yu Yaqian1, Zhang Chuanliang1, Zeng Guowei1
1Peking University Shenzhen Hospital Shenzhen, Guangdong, China.
Trials
|January 26, 2026
概括
一个新的Z形仰卧姿势可能会减少机器人辅助激进前列腺切除术 (RARP) 的并发症. 这项研究将其与标准RARP定位进行比较,以提高前列腺癌手术期间的患者安全性和舒适性.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 手术创新 在外科创新.
- 患者安全 患者安全
背景情况:
- 前列腺癌是全球男性常见的恶性瘤.
- 机器人辅助激进前列腺切除术 (RARP) 是一种标准的治疗方法.
- 目前的RARP定位 (石切割,的Trendelenburg) 会导致神经损伤,眼内压力升高 (IOP) 和其他并发症.
研究的目的:
- 为RARP.介绍和评估一个新的"Z形仰卧姿势".
- 评估Z形卧卧姿在减少外科手术后并发症方面的有效性.
- 为了比较Z形卧式和标准RARP姿势之间的患者舒适度和结果.
主要方法:
- 一个单中心,随机对照试验,涉及78名接受RARP的患者.
- 患者被随机分配到标准RARP定位或Z形卧卧姿.
- Z形卧卧姿包括特定的部/膝盖曲,腿部绑架,Trendelenburg倾斜和子支架;结果包括神经损伤,IOP和与压力相关的损伤.
主要成果:
- 该研究旨在确定外围神经损伤的发生率作为主要结果.
- 其次性结局包括手术内内血压,皮肤/深静脉血栓,疼痛和压力损伤.
- 统计分析将遵循治疗意图 (ITT) 方法.
结论:
- 建议Z形卧卧姿作为RARP的潜在更安全的替代方案.
- 这项研究旨在验证这一立场,以减少并发症并保持外科疗效.
- 这项创新旨在提高前列腺癌手术期间和之后的患者福祉.
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